diff --git a/TSRM/TSRM.c b/TSRM/TSRM.c
index a39564b893..5618849d4d 100644
--- a/TSRM/TSRM.c
+++ b/TSRM/TSRM.c
@@ -744,10 +744,17 @@ TSRM_API size_t tsrm_get_ls_cache_tcb_offset(void)
 #elif defined(__aarch64__)
 	size_t ret;
 
+# ifdef __APPLE__
+	// Points to struct TLVDecriptor for _tsrm_ls_cache in macOS.
+	asm("adrp %0, #__tsrm_ls_cache@TLVPPAGE\n\t"
+	    "ldr %0, [%0, #__tsrm_ls_cache@TLVPPAGEOFF]"
+	     : "=r" (ret));
+# else
 	asm("mov %0, xzr\n\t"
 	    "add %0, %0, #:tprel_hi12:_tsrm_ls_cache, lsl #12\n\t"
 	    "add %0, %0, #:tprel_lo12_nc:_tsrm_ls_cache"
 	     : "=r" (ret));
+# endif
 	return ret;
 #else
 	return 0;
diff --git a/ext/opcache/jit/zend_jit.c b/ext/opcache/jit/zend_jit.c
index 3427ae16a8..e7226aae6d 100644
--- a/ext/opcache/jit/zend_jit.c
+++ b/ext/opcache/jit/zend_jit.c
@@ -4055,8 +4055,12 @@ ZEND_EXT_API void zend_jit_unprotect(void)
 	if (!(JIT_G(debug) & (ZEND_JIT_DEBUG_GDB|ZEND_JIT_DEBUG_PERF_DUMP))) {
 		int opts = PROT_READ | PROT_WRITE;
 #ifdef ZTS
+  /* TODO: EXEC+WRITE is not supported in macOS. Removing EXEC is still buggy as
+   * other threads, which are executing the JITed code, would crash anyway. */
+# ifndef __APPLE__
 		/* Another thread may be executing JITed code. */
 		opts |= PROT_EXEC;
+# endif
 #endif
 		if (mprotect(dasm_buf, dasm_size, opts) != 0) {
 			fprintf(stderr, "mprotect() failed [%d] %s\n", errno, strerror(errno));
diff --git a/ext/opcache/jit/zend_jit_arm64.dasc b/ext/opcache/jit/zend_jit_arm64.dasc
index 6961f53398..62893a822f 100644
--- a/ext/opcache/jit/zend_jit_arm64.dasc
+++ b/ext/opcache/jit/zend_jit_arm64.dasc
@@ -184,6 +184,14 @@ const char* zend_reg_name[] = {
 
 #if ZTS
 static size_t tsrm_ls_cache_tcb_offset = 0;
+# ifdef __APPLE__
+struct TLVDescriptor {
+	void*       (*thunk)(struct TLVDescriptor*);
+	uint64_t    key;
+	uint64_t    offset;
+};
+typedef struct TLVDescriptor TLVDescriptor;
+# endif
 #endif
 
 /* By default avoid JITing inline handlers if it does not seem profitable due to lack of
@@ -483,10 +491,27 @@ static int logical_immediate_p (uint64_t value, uint32_t reg_size)
 ||	}
 |.endmacro
 
+// Safe memory load/store with an unsigned 64-bit offset.
+|.macro SAFE_MEM_ACC_WITH_64_UOFFSET, ldr_str_ins, op, base_reg, offset, tmp_reg
+||	if (((uintptr_t)(offset)) > LDR_STR_PIMM64) {
+|		LOAD_64BIT_VAL tmp_reg, offset
+|		ldr_str_ins op, [base_reg, tmp_reg]
+||	} else {
+|		ldr_str_ins op, [base_reg, #(offset)]
+||	}
+|.endmacro
+
 |.macro LOAD_TSRM_CACHE, reg
+||#ifdef __APPLE__
+|	.long 0xd53bd071 // TODO: hard-coded: mrs TMP3, tpidrro_el0
+|	and TMP3, TMP3, #0xfffffffffffffff8
+|	SAFE_MEM_ACC_WITH_64_UOFFSET ldr, TMP3, TMP3, (((TLVDescriptor*)tsrm_ls_cache_tcb_offset)->key << 3), TMP1
+|	SAFE_MEM_ACC_WITH_64_UOFFSET ldr, reg, TMP3, (((TLVDescriptor*)tsrm_ls_cache_tcb_offset)->offset), TMP1
+||#else
 |	.long 0xd53bd051 // TODO: hard-coded: mrs TMP3, tpidr_el0
 ||	ZEND_ASSERT(tsrm_ls_cache_tcb_offset <= LDR_STR_PIMM64);
 |	ldr reg, [TMP3, #tsrm_ls_cache_tcb_offset]
+||#endif
 |.endmacro
 
 |.macro LOAD_ADDR_ZTS, reg, struct, field